Yes, the hassle next to the commute. Hobby, children, doctors, supermarket. However, I would put aside the thought of where friends live. Priorities change quickly, and family and house/garden take on a completely different importance than friends, who eventually also focus on family. Edit: Sorry, overlapped.
I would proceed exactly the other way around: I don't find the commute to work that important. Because you have to go to work, you just do it. Even if it’s more than half an hour. If friends are only difficult to reach and priorities shift, the circle of friends/acquaintances thins out. With truly good, old friends the distance doesn't matter, with acquaintances, sports friends, hobbies etc., it’s important to me that it’s easy to reach. Someone wrote something about cycling: yes, with an e-bike absolutely no problem. I rode 20 km one way for quite some time with a normal (but good) bike. That took 65 minutes per way, but it provided daily exercise, better well-being and health, and possibilities for quick shopping, more flexibility in time management after work (straight to friends or similar). Around here, with an e-bike everything up to just under 40 km one way is done. That is really no problem. If there is interest in doing the commute by bike, then the route and surroundings are important: can you take nice side roads and shortcuts through parks and green spaces or do you just ride through traffic? There are more nice routes than one/Google Maps/komoot think; I would do a test ride there. Especially without children, you can definitely afford a longer commute. It's no problem, I think. In a car I would find it really annoying, on a bike it can be a true luxury. (I chose my new job, among other things, based on the commute distance. I didn’t want under 10 km. Now I have 5 km one way and that is too much to really feel like it’s a short commute and too little to really get going and warm up the muscles.)