The biggest difference between the providers lies in the different equipment and the different construction specifications. Is the foundation slab included or not? Up to what depth are earthworks included? Which sanitary fixtures are included as standard? How many power outlets, lamp sockets, etc. are included? Which stair coverings, wood (which kind?), steel stairs, concrete stairs with tiles/granite/wood? Is underfloor heating included in the price or not? What kind of roof covering, clay or concrete? Which windows with which values (security class, for example)? Front door made of plastic or aluminum? What wall construction (these also differ significantly among prefabricated houses or solid houses)? What energy standard is achieved? What kind of heating is installed? Is there a controlled residential ventilation system? According to the construction description, what must be carried out "on site"? Can the floor plan be individually planned/changed without additional costs for extra planning effort? These are just a few examples. The construction specification consists of what feels like thousands of different things, each of which can vary individually from provider to provider. That is why prices differ significantly from one solid house provider to another, as well as from one prefabricated house provider to another. The decision between a prefabricated house and a solid house is therefore not the main cost criterion, but rather the entire construction specification itself. And that makes it so difficult to compare the various providers—regardless of the construction method. It is a real jungle to wade through. However, we have also experienced that prefabricated houses seem to be somewhat more expensive, but we have not compared that precisely enough to specify it exactly.
The decision for a construction method should therefore primarily not be based on costs. At the same standard, they do not differ too much, at least if you rely on the "major" providers. In my experience, small solid-house builders are cheaper than the big ones. In the end, we decided on construction with an architect and individual contract award (solid construction) because it was clearly the cheaper way for us (cheaper than construction with a large general contractor or small general contractor). My cousin is building a timber-frame house. He had the shell built by a local carpenter and awarded the remaining trades individually. That was also cheaper than going with a large prefabricated house builder. Nevertheless, his house was significantly more expensive than ours, which of course is also due to the fact that he is building to a different standard (we energy saving ordinance, he KFW40).
Which construction method it will be is simply decided by personal preference. Some can do more with wood, others prefer the classic stone house.