My main concern with the air conditioning was to create comfortable temperatures in the bedroom at night.
We have a bedroom facing south, and despite shading, it heats up quite a bit at an outside temperature of 30 degrees... so much so that in the first year I could barely sleep or not sleep at all. So the air conditioner was purchased and installed in the bedroom. The problem now is that if I only run the air conditioner for a few hours a day, the bedroom becomes relatively warm again at night... as Saruss correctly noted, the law of conservation of energy... so the air conditioner has to run until the room including furniture, etc. is really cooled down, which in our case means about 16 hours a day... so that I can turn off the air conditioner for the remaining 8 hours and sleep... in the morning after getting up, it is turned on again.
In doing so, I have noticed that the system (with 16 hours of operation) can supply the entire upper floor with cold air, but the other rooms heat up much faster again, although there is a temperature drop of 3-4 degrees during the day.
Hence the initial statement again... yes, it is possible to cool an entire floor with a single air conditioning unit. Whether it is inefficient is another matter. That is why I am also considering simply installing a ceiling cassette in the upper floor in the stairwell and then purchasing a 7 kW (or maybe 9 kW) system. This should then be able to cool the whole house.