Thank you very much for the many responses. I will try to clarify a few open points.
Yes, the 45km also intimidate us a bit, but you have to say that after 5km you are on the highway and then you can practically drive straight to the workplace. You can be at the location (without traffic jam) within 30 minutes.
Changing workplaces is actually not an option for either of us.
The desire to have children is not conclusively settled, but this is not due to our decision-making ability, rather other "health-related" reasons.
The question is of course - what do we want with 5 rooms, 140 sqm without children.
Likewise, alternative thoughts come up for us, simply renting a house closer to the workplace, about 15-20km away. Here the prices in the area are between 900-1100€ for similar properties, if they are not new buildings. This actually seems to be an option for us (even though we do not own the property), to live a financially freer life and not to "lose" equity.
What is your opinion on this?