If the shower must be located at the top right (that is the only thing that is the same in all your plans), you might swap the bathtub and shower in Kaho's proposal.
Definitely Katja's version. Versions 1-3 look "awkward." When I imagine entering the bathroom in my mind, none of the three versions are nice.
Sewage cannot be the problem. The toilet is the only thing limited to such a distance because of the downpipe, etc. but that also moves around the room in the three versions. You can shift the shower and tub quite a bit within the floor.
We have 155 (internal dimension) by 110 with a side entrance and side showerhead. Even then, a bit splashes out. Not bad but we always put a towel in front. I believe if the entrance were not on the side, you would have to wipe the bathroom after showering